AM Pharma
  • Home
  • About Us
    • About AM-Pharma
    • Management Team
    • Supervisory Board
    • Careers
  • Our approach
    • Our Product and MOA
    • Acute Kidney Injury (AKI)
    • Our AKI Pipeline
      • SA-AKI
      • COVID-19 and AKI
      • CKD and AKI
      • CSA-AKI
  • Partnering
  • Investors
  • Media Centre
    • Press Releases
    • Publications
  • Contact
  • Menu Menu

Home > Programs

Programs

AM-Pharma is a clinical stage biopharmaceutical company developing Alkaline Phosphatase biologic therapies.

Alkaline Phosphatase (AP) has a key role in protecting organs against inflammation and tissue damage, acting as a detoxifying agent by dephosphorylating pro-inflammatory substances.

Acute Kidney Injury

In our lead program, we are preparing for a Phase III pivotal study and subsequent commercialization of recAP as a transformative treatment for Acute Kidney Injury (AKI).

Learn more

Inflammatory Bowel Disease

We are developing an oral formulation of recAP as a potential treatment option for Ulcerative Colitis, in which patients show reduced AP expression in the gut.

Learn more

Hypophosphatasia

We are exploring the use of recAP in the treatment of Hypophosphatasia (HPP), a metabolic orphan disease which affects bone formation and calcification.

Learn more

RECAP

We have developed recombinant human Alkaline Phosphatase (recAP), constructed from two human isoforms of AP, as an innovative disease modifying therapeutic. recAP is optimized for high stability and activity and has been evaluated in clinical trials.

Molecular model of recombinant Alkaline Phosphatase (AP), recAP, a homodimer consisting of the activity domains from human intestinal AP (displayed in white) and the stability or crown domains from placental AP (red). (courtesy of Prof J.L. Millan, Sanford Burnham Institute Medical Research, UCSD, La Jolla, CA)

  • Privacy Policy
© AM-Pharma B.V.
Website by BTTR
linkedin
Scroll to top

We use cookies to help us improve our website by collecting and reporting information on how you use it. For more information about how we use cookies please see our Cookies Policy

AcceptReject


How we use cookies

We may request cookies to be set on your device. We use cookies to let us know when you visit our websites, how you interact with us, to enrich your user experience, and to customize your relationship with our website.

Click on the different category headings to find out more. You can also change some of your preferences. Note that blocking some types of cookies may impact your experience on our websites and the services we are able to offer.

Essential Website Cookies

These cookies are strictly necessary to provide you with services available through our website and to use some of its features.

Because these cookies are strictly necessary to deliver the website, refuseing them will have impact how our site functions. You always can block or delete cookies by changing your browser settings and force blocking all cookies on this website. But this will always prompt you to accept/refuse cookies when revisiting our site.

We fully respect if you want to refuse cookies but to avoid asking you again and again kindly allow us to store a cookie for that. You are free to opt out any time or opt in for other cookies to get a better experience. If you refuse cookies we will remove all set cookies in our domain.

We provide you with a list of stored cookies on your computer in our domain so you can check what we stored. Due to security reasons we are not able to show or modify cookies from other domains. You can check these in your browser security settings.

Google Analytics Cookies

These cookies collect information that is used either in aggregate form to help us understand how our website is being used or how effective our marketing campaigns are, or to help us customize our website and application for you in order to enhance your experience.

If you do not want that we track your visit to our site you can disable tracking in your browser here:

Other external services

We also use different external services like Google Webfonts, Google Maps, and external Video providers. Since these providers may collect personal data like your IP address we allow you to block them here. Please be aware that this might heavily reduce the functionality and appearance of our site. Changes will take effect once you reload the page.

Google Webfont Settings:

Google Map Settings:

Google reCaptcha Settings:

Vimeo and Youtube video embeds:

Other cookies

The following cookies are also needed - You can choose if you want to allow them:

Privacy Policy

You can read about our cookies and privacy settings in detail on our Privacy Policy Page.

Privacy Policy
Accept settingsHide notification only